Complete Pathologic Response After Neoadjuvant Chemoradiotherapy for Esophageal Cancer Is Associated With Enhanced Survival
نویسندگان
چکیده
منابع مشابه
Effect of neoadjuvant chemoradiotherapy on pathologic stage and survival in patients with locally advanced esophageal cancer.
4032 Background: The strongest predictor of survival in patients with locally advanced esophageal cancer treated with primary surgical resection is stage. This study aimed to determine if surgical stage after pre-operative chemoradiotherapy predicted a similar survival pattern. METHODS Patients (n=42) received cisplatin, 5-FU and radiotherapy (RT) followed by esophagectomy. Pre- and post-trea...
متن کاملClinical parameters predicting pathologic complete response following neoadjuvant chemoradiotherapy for rectal cancer.
INTRODUCTION Preoperative chemoradiotherapy (CRT), followed by total mesorectal excision, has become the standard of care for patients with clinical stages II and III rectal cancer. Patients with pathologic complete response (pCR) to preoperative CRT have been reported to have better outcomes than those without pCR. However, the factors that predict the response to neoadjuvant CRT have not been...
متن کاملPositron emission tomography for predicting pathologic response after neoadjuvant chemoradiotherapy for locally advanced rectal cancer.
PURPOSE To investigate whether before and after chemoradiotherapy (CRT) positron emission tomography (PET) predict for pathologic response after preoperative CRT in patients with locally advanced rectal adenocarcinoma. METHODS Thirty-five patients who underwent pre-CRT and post-CRT PET scans before surgery were included. All patients were staged with endoscopic ultrasound or high resolution C...
متن کاملNeoadjuvant chemoradiotherapy for esophageal cancer: is it worthwhile?
BACKGROUND With promising results from several institutions, many centers began treating patients with esophageal cancer with neoadjuvant chemoradiotherapy (NC) followed by esophagectomy. This approach is demanding for the patient and has not been proved to be better than esophagectomy alone. OBJECTIVE To assess survival time and measures of quality of life associated with NC. DESIGN A retr...
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Background: This study assessed the optimal timing of computed tomography for detection of metastatic disease in locoregional lymph nodes in patients with rectal cancer who have undergone chemoradiotherapy. Materials and Methods: This observational retrospective study was performed in a single institution. All patients with locally advanced rectal cancer treated with chemoradiotherapy, followed...
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ژورنال
عنوان ژورنال: The Annals of Thoracic Surgery
سال: 2009
ISSN: 0003-4975
DOI: 10.1016/j.athoracsur.2008.11.001